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July 3, 2023 – BRAZIL – 52 year old singer and composer Frank Aguiar is married to 31 year old Caroline Aguiar, who revealed on social media on her birthday that she had Stevens-Johnson Syndrome that “burns the body” and was hospitalized in the ICU for 10 days, almost died.

This is now a recognized reaction to Pfizer & Moderna COVID-19 mRNA Vaccines:

October 2022 – 22 year old Charish Chambers worked as CNA for the VA. She developed Stevens-Johnson Syndrome after her COVID-19 vaccine. She now suffers from Neuropathy.

Jan. 2023 – Julie Mitchell Peel is a photographer, her daughter Lia was diagnosed with Stevens-Johnson Syndrome/TEN. She lost 74% of her skin and was intubated but has recovered.

What Is Stevens-Johnson Syndrome?

Stevens-Johnson syndrome (SJS) is an acute hypersensitivity reaction that causes extensive necrosis of the mucous membrane and skin.

SJS results from a cytotoxic immune reaction in keratinocytes, which leads to widespread keratinocyte apoptosis (cell death).

Although bacterial and viral infections are considered causative factors in the syndrome, medications also are thought to be a major cause.

SJS has also been reported with vaccines: influenza, measles, varicella, tetanus.

Often described as SJS/TEN (TEN = toxic epidermal necrolysis)

• It is SJS if < 10% of the body surface is involved
• It is TEN if > 30% of the body surface is involved

According to earlier studies, the prevalence of SJS is fewer than 1 to 2 cases per million people per year.

Mortality rate is approximately 25-30%.

Saudi Arabia Reported First SJS Case after Pfizer mRNA

• Elboraey and Essa reported the 1st SJS case after Pfizer mRNA in Oct.2021:
• It was a middle aged female in Saudi Arabia
• She developed lesions 5 days after 2nd Pfizer dose (nothing after 1st dose!)
• they theorized Pfizer mRNA stimulates immune cells, cytotoxic T cells and Natural killer cells that secrete granulysin which destroys cells in skin and mucous membrane by dysregulation of specific protein pathways.

South Korea Reported First SJS Case after Pfizer Booster

• Mihn-Sook Jue et al reported another case:
• 20 year old South Korean woman had 3rd Pfizer COVID-19 mRNA vaccine
• next day she came to ER with fever & skin lesions (had no issues with dose 1 or 2)
• she needed 5 weeks of IV steroids.

Croatian Doctors Take a Shot at “Anti-vaxxers” and Fail 

• A hilarious 2022 paper by Croatian doctors Dodig et al:
• “SJS (clinical) presentation is impressive and anti-vaxxers’ misinformation regarding COVID-19 vaccination campaign was focused on SJS to increase vaccine hesitancy”
• Conclusion: “SJS after COVID-19 vaccination seems to be a possible but exceedingly rare adverse drug reaction. The potential signal identified in our short analysis, regarding Moderna vaccine, deserves further in-depth analysis and could be due to the substantially higher dose used by the Moderna vaccine”

USA (Minnesota)

• Padniewski et al. reported a 46 yo Ethiopian woman who had 1st Moderna mRNA
• she presented in ER 3 days later with skin and mucosal lesions

Australia

• Stanley et al – Doctors in a burn unit in a Hospital in Sydney, Australia published:
• 7-fold increase in SJS since start of COVID-19 vaccination
• 8 patients all mRNA vaxxed (3 were double, 4 were triple, 1 was quadruple jabbed
• Theorized that spike protein may bind T helper type 1 cells leading to clonal expansion of cytotoxic T cells that may abnormally release granules that cause apoptosis in skin
• Although theorized that spike protein could “prime” the immune system for a future drug to cause SJS/TEN.

AstraZeneca COVID-19 Vaccine Did this Too 

• Gouveia et al, Brazilian researchers reported SJS with AstraZeneca COVID-19 vaccine also
• 40 year old black woman had 1st AstraZeneca COVID-19 jab, 2 days later presented with this

My Take…

Stevens-Johnson Syndrome was a rare hypersensitivity reaction, reported to occur with over 200 drugs, including influenza vaccines (flu shots) and other vaccines.

Since COVID-19 vaccines rolled out, there has been a 7-fold (700%) increase in SJS.

SJS is now a known reaction to Pfizer & Moderna COVID-19 mRNA vaccines, with 296 cases reported to WHO database VigiAccess.

Clinical Picture:

• Mortality rate of SJS/TEN can be up to 25-30%
• starts with fever, cough, lymph nodes
• rash first appears on mouth (look for lip sores), neck and arms
• can spread all over the body with blisters and crusting
• skin may get detached
• may involve mucosa: esophagus, vagina, rectum and the eyes (risk of blindness)
• disfiguring scars may develop

SJS/TEN is evidence of a dysfunctional immune system response.

The theory is that this is a delayed type hypersensitivity reaction, T-cell mediated, which can occur anywhere from 6 hours to weeks after mRNA vaccine injection.

The COVID-19 Vaccine spike protein is expressed on keratinocytes in the skin and stimulates an abnormal immune response resulting in cytotoxic T-cells that release enzymes that lead to apoptosis (cell death) in the skin and mucous membranes.

You can get this reaction with any mRNA dose, even if you had no reaction to previous doses, this is probably due to the batch to batch variability of the contents of mRNA vials.

SJS/TEN is a MEDICAL EMERGENCY that responds to IV steroids, but after getting immediate medical attention for this reaction, detoxing the spike protein is still very important!

Spike protein detox is the usual:

• Spike breakdown: Nattokinase, Bromelain (Serrapeptase, Lumbrokinase)
• Spike binding: Quercetin, Olive Leaf, Black Seed, Curcumin, Dandelion extract
• Antioxidants: NAC, Taurine, Vitamin C, Resveratrol, CoQ10
• Immune Support: Vitamin D, Zinc, Magnesium, Selenium, Melatonin, etc
• Autophagy: 3-day water fast

(Special thanks to Nashville Angela on Twitter for bringing attention to these painful mRNA vaccine injury cases and trying to wake people up!)

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Dr. William Makis is a Canadian physician with expertise in Radiology, Oncology and Immunology. Governor General’s Medal, University of Toronto Scholar. Author of 100+ peer-reviewed medical publications.

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